Académie royale de Médecine de Belgique

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Résumé de Paul Barrow (Séance du 17.12.2011)

 

NEW VIRAL PATHOGENS FROM WILDLIFE

par  P. A. BARROW (University of Nottingham – G.B.), invité.      

The world is changing and many of the changes are directly or indirectly attributable to increasing human population. The increase in human numbers results in environmental degradation and pollution. Increasing meat consumption by many developing countries results in changes in land use and deforestation. These factors combine to increase the frequency with which mankind and his livestock make contact with wild animal species and arthropod vectors with which they have not previously had contact. Over the past 20 years there have been a number of incidences where new viruses with a wildlife source have been transmitted to livestock or man and identified. Some of these incidents will be described. Many new viruses have been detected by a combination of specific or random amplification of nucleic acid signals either from tissues or from crude tissue cultures, followed by high through-put sequencing. Microarrays are also being increasingly used where generic oligonucleotides can detect the presence of a new virus related to existing viral taxa which can then also be sequenced. It seems likely that, with climatic changes which can induce alterations in host and vector distribution, many changes in disease distribution will continue to occur for some years.

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